Current state of hormone replacement therapy: the case for using trimegestone

Author: Wahab May   Al-Azzawi Farook  

Publisher: Future Medicine

ISSN: 1745-5057

Source: Women's Health, Vol.2, Iss.4, 2006-07, pp. : 539-550

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Abstract

Estrogen deficiency has a negative impact on the quality of life of postmenopausal women and is associated with vasomotor symptoms, insomnia and emotional lability. Other manifestations of estrogen deficiency include dry skin, dry vagina and dyspareunia, in addition to bone loss. Estrogen replacement effectively reverses these changes. The only indication for the administration of a progestogen is to protect the postmenopausal uterus against the potential development of endometrial hyperplasia and carcinoma.