Reversible Panhypogammaglobulinemia Associated with Phenytoin Treatment

Author: Pereira Luis F.   Sanchez Juan F.  

Publisher: Informa Healthcare

ISSN: 0036-5548

Source: Scandinavian Journal of Infectious Diseases, Vol.34, Iss.10, 2002-10, pp. : 785-787

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Abstract

We report the case of a 24-y-old woman who presented with repeated episodes of otitis due to panhypogammaglobulinemia and low levels of mature CD19 + B cells (84 cells/μl) associated with phenytoin treatment. Lymphocyte subpopulations and immunoglobulin levels need to be monitored if symptoms indicating immunodeficiency occur after the initiation of this treatment.