Author： Viale Pierluigi Pagani Leonardo Cristini Francesco Stefini Roberto Bergomi Riccardo Colombini Paolo Carosi Giampiero
Publisher： Informa Healthcare
ISSN： 0036-5548
Source： Scandinavian Journal of Infectious Diseases, Vol.34, Iss.6, 2002-06, pp. : 456-459
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Abstract
We report our experience with linezolid in the treatment of 5 patients with central nervous system infections subsequent to neurosurgical interventions. In all cases, initial antimicrobial treatment regimens, including a glycopeptide, either failed or were associated with significant adverse events. The good clinical outcome and the absence of significant side-effects associated with linezolid suggest that it may be an attractive alternative for the treatment of central nervous system infections, particularly in settings characterized by a high incidence of multiresistant Gram-positive pathogens.
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