Pseudotumour Cerebri Syndrome and Levofloxacin Therapy: A Case Report

Author: Cellini Mauro   Strobbe Ernesto   Gizzi Corrado   Campos Emilio C.  

Publisher: Informa Healthcare

ISSN: 0165-8107

Source: Neuro-Ophthalmology, Vol.34, Iss.5-6, 2010-12, pp. : 358-360

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Abstract

Many drugs, including quinolone antibiotics, have been implicated in the aetiology of pseudotumour cerebri. We here report the case of an 18-year-old male of high body mass index who developed pseudotumour cerebri after treatment with oral levofloxacin for broncho-pneumonia. After 5 days of treatment, his general condition improved but he started to complain of headache, intermittent vomiting, tinnitus in the left ear, blurred vision, photophobia, and intermittent horizontal diplopia. The fundus oculi examination revealed bilateral papilloedema. All the symptoms resolved within 2 weeks after levofloxacin withdrawal. This case raises the possibility that quinolone antibiotics can cause pseudotumour cerebri.