Author： Bednenko V. S. Matyushev T. V.
Publisher： MAIK Nauka/Interperiodica
ISSN： 0362-1197
Source： Human Physiology, Vol.30, Iss.3, 2004-05, pp. : 336-342
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Abstract
According to the concept of separate description of the passive and active regulation of circulation in humans, a model of the lowest hierarchical level is suggested implying subsequent introduction of the elements of active regulatory subsystems into it. According to the principles of this concept, a formalized description of the model of human central hemodynamics is presented. The model allows prediction of the effect of gravitation on the function of the circulatory system under antiorthostatic conditions. The basic structures for the description of circulation regulatory mechanisms have been taken from N.M. Amosov's and R.D. Grigoryan's models of regulation. The use of Amosov's scheme of circulation regulation makes it possible to take into account the effect of the activity of baroreceptor-mediated regulation on compensatory responses of the body within the nervous control loop. The model allows simulation of the redistribution of blood flows in different parts of the body and assessment of the efficiency of blood storage under antiorthostatic conditions without experiments with human volunteers.
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