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Three-component condensation of 2-naphthylamine with aromatic aldehydes and 5-(2-furyl)-1,3-cyclohexanedione

Author： Kozlov N. Gusak K. Skatetskii V.

Publisher： MAIK Nauka/Interperiodica

ISSN： 1070-4280

Source： Russian Journal of Organic Chemistry, Vol.42, Iss.1, 2006-01, pp. : 112-117

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

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Abstract

Three-component condensation of 5-(2-furyl)-1,3-cyclohexanedione with 2-naphthylamine and aromatic or heteroaromatic aldehydes afforded 12-aryl(hetaryl)-9-(2-furyl)-7,8,9,10,11,12-hexahydrobenzo[a]-acridin-11-ones possessing two asymmetric carbon atoms (C⁹ and C¹²). The products were found to be formed as mixtures of diastereoisomers.

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