3-aryl(alkyl)quinazoline-2,4(1H,3H)-diones and their alkyl derivatives

Author： Shestakov A.   Sidorenko O.   Bushmarinov I.   Shikhaliev Kh.   Antipin M.  

Publisher： MAIK Nauka/Interperiodica

ISSN： 1070-4280

Source： Russian Journal of Organic Chemistry, Vol.45, Iss.11, 2009-11, pp. : 1691-1696

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Abstract

Two-stage reaction of methyl anthranilate with aryl(alkyl) isocyanates in keeping with the quantumchemical calculations and XRD analysis resulted in 3-aryl(alkyl)quinazoline-2,4(1H,3H)-diones that by treatment with alkyl halides, phenacyl bromides, esters and amides of chloroacetic acid were converted into the corresponding 1-alkyl derivatives.

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