Author： Ryzhavskii B. Ya. Vasileva E. V. Eremenko I. R. Sapozhnikov Yu. A. Sokolova T. V. Rudman Yu. Yu.
Publisher： Springer Publishing Company
ISSN： 0007-4888
Source： Bulletin of Experimental Biology and Medicine, Vol.137, Iss.6, 2004-06, pp. : 628-631
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Abstract
We examined the offspring of rats receiving sustanon with testosterone derivatives on day 19 of pregnancy. At the age of 1 month, these rats differed from control animals in the indexes of higher nervous activity. The relative weight of the brain increased in 54-day-old rats receiving the hormone. Female rats were characterized by increased sudanophilia of the white matter in cerebellar hemispheres and high RNA content in layer V neurons of the parietal lobe, increased volume of nuclei in hippocampal neurons, weight of the ovaries (tendency), size of the largest follicles, and high activity of 3β-ol-steroid dehydrogenase. The weight of the adrenal glands and 3β-ol-steroid dehydrogenase activity in adrenocortical cells of the fascicular zone increased in male rats.
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