Author： Fedotova Yu. O. Goncharov N. P. Sapronov N. S.
Publisher： Springer Publishing Company
ISSN： 0007-4888
Source： Bulletin of Experimental Biology and Medicine, Vol.138, Iss.1, 2004-07, pp. : 54-57
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
Abstract
We studied the effect of repeated intraperitoneal treatment with dehydroepiandrosterone in doses of 0.1 and 0.7 mg/kg on conditioned-response activity and behavior of adult male rats. The effect of dehydroepiandrosterone on learning was estimated in conditioned active and passive avoidance response paradigms. Chronic administration of dehydroepiandrosterone in low and high doses had no effect on retention of conditioned passive avoidance response in adult male rats 24 h after learning. However, chronic administration of dehydroepiandrosterone in low dose impaired acquisition of the conditioned active avoidance response. It should be emphasized that chronic administration of dehydroepiandrosterone in high dose did not modulate acquisition and retention of this reaction.
Related content
Access to resources
Recommend
By Romanova G. Shakova F. Gorbatov V. Kvashennikova Yu. Davydova T.
Bulletin of Experimental Biology and Medicine, Vol. 149, Iss. 3, 2010-09 ,pp. :
By Graf A. Maklakova A. Krushinskaya Ya. Sokolova N.
Bulletin of Experimental Biology and Medicine, Vol. 142, Iss. 1, 2006-07 ,pp. :