Author： Teplyuk N. Dukhanin A. Ogurtsov S. Belysheva T.
Publisher： Springer Publishing Company
ISSN： 0007-4888
Source： Bulletin of Experimental Biology and Medicine, Vol.140, Iss.3, 2005-09, pp. : 323-325
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Abstract
Prednisolone in therapeutic concentrations blocks Ca2+ channels of lymphocyte plasma membranes and prevents arachidonic acid-induced Ca2+ entry into the cells. Glucocorticoid virtually did not modulate arachidonic acid-stimulated release of Ca2+ from intracellular stores. No appreciable effect of the hormone on mitogen-induced changes in the intracellular content of cAMP was detected.
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