Synthesis of a New Polyheterocyclic System — Pyrazolo[5′,1′:2,3]pyrimido[1,6-a]benzimidazole

Author： Dzvinchuk I.   Lozinskii M.  

Publisher： Springer Publishing Company

ISSN： 0009-3122

Source： Chemistry of Heterocyclic Compounds, Vol.41, Iss.11, 2005-11, pp. : 1419-1423

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Abstract

Cyanoethylhydrazones of 2-aroylmethyl-1H-benzimidazoles undergo recyclization on reaction with trifluoroacetyl anhydride to give 3-aryl-1-cyanoethyl-5-(2-trfluoroacetaminoanilino)pyrazoles. The recyclization products may be cyclized with closing of the benzimidazole ring in two ways: with formation of 1-(5-pyrazolyl)benzimidazoles or 5,6-dihydroderivatives of a new polyheterocyclic system — pyrazolo[5′,1′: 2,3]pyrimido[1,6-a]benzimidazole.

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