Synthesis of new 2-amino-5-hydroxymethyl-2-thiazolines

Author: Trofimova T.   Pushin A.   Proshin A.   Stash A.   Mandrugin A.   Fedoseev V.   Proskuryakov S.  

Publisher: Springer Publishing Company

ISSN: 0009-3122

Source: Chemistry of Heterocyclic Compounds, Vol.43, Iss.3, 2007-03, pp. : 370-376

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Abstract

A simple and convenient method is proposed for the synthesis of 2-amino-5-hydroxymethylthiazolines with various substituents in the amino group, which is based on hydrolysis of the corresponding 5-halomethyl derivatives of thiazoline in the presence of divalent lead oxide.