ZRX1, the first EGFR inhibitor-capecitabine based combi-molecule, requires carboxylesterase-mediated hydrolysis for optimal activity

Author: Ait-Tihyaty Maria   Rachid Zakaria   Larroque-Lombard Anne-Laure   Jean-Claude Bertrand  

Publisher: Springer Publishing Company

ISSN: 0167-6997

Source: Investigational New Drugs, Vol.31, Iss.6, 2013-12, pp. : 1409-1423

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Abstract