Direct Inhibition and Down-regulation by Uremic Plasma Components of Hepatic Uptake Transporter for SN-38, an Active Metabolite of Irinotecan, in Humans

Author: Fujita Ken-ichi   Sugiura Tomoko   Okumura Hidenori   Umeda Saki   Nakamichi Noritaka   Watanabe Yusuke   Suzuki Hiromichi   Sunakawa Yu   Shimada Ken   Kawara Kaori   Sasaki Yasutsuna   Kato Yukio  

Publisher: Springer Publishing Company

ISSN: 0724-8741

Source: Pharmaceutical Research, Vol.31, Iss.1, 2014-01, pp. : 204-215

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Abstract