Author： Kovyazina I.V. Tsentsevitsky A.N. Nikolsky E.E.
Publisher： Springer Publishing Company
ISSN： 0090-2977
Source： Neurophysiology, Vol.34, Iss.2-3, 2002-03, pp. : 163-164
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Abstract
We investigated the effects of repetitive high-frequency (10 sec-1) nerve stimulation on the time course of evoked and miniature end-plate currents (EPC and mEPC, respectively) in the frog neuromuscular junction. The data obtained indicate that at a physiological Ca2+ level in the bath medium, 10 sec-1 stimulation results in prolongation of the growth phase of multiquantum EPC without any effect on the mEPC time course. It is concluded that timing of acetylcholine quantum secretion may be affected by high-frequency stimulation.
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