Shapes of Mixed Phospholipid Vesicles

Author: Paredes-Quijada Gerardo   Aranda-Espinoza Helim   Maldonado Amir  

Publisher: Springer Publishing Company

ISSN: 0092-0606

Source: Journal of Biological Physics, Vol.32, Iss.2, 2006-10, pp. : 177-181

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Abstract

We studied the shape of phospholipid vesicles prepared by hydration of a mixture of phosphatidylcholine (SOPC) and phosphatidylserine (SOPS) in different proportions. The aim of the work is to obtain some insight into the influence of the chemical composition of a biomembrane on its shape. The optical microscopy results show that the shape of the vesicles depend on the SOPC:SOPS composition. For low SOPS contents, coiled cylindrical vesicles are observed. The results suggest that specific compositions of the SOPC:SOPS vesicles produce some spontaneous curvature on the membrane and then a coiling instability.