Trabectedin (ET-743, Yondelis™) is a substrate for P-glycoprotein, but only high expression of P-glycoprotein confers the multidrug resistance phenotype

Author: Beumer Jan-Hendrik   Buckle Tessa   Ouwehand Mariet   Franke Niels   Lopez-Lazaro Luis   Schellens Jan   Beijnen Jos   Tellingen Olaf  

Publisher: Springer Publishing Company

ISSN: 0167-6997

Source: Investigational New Drugs, Vol.25, Iss.1, 2007-02, pp. : 1-7

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Abstract