Sandwich-cultured hepatocytes: utility for in vitro exploration of hepatobiliary drug disposition and drug-induced hepatotoxicity

By De Bruyn Tom   Chatterjee Sagnik   Fattah Sarinj   Keemink Janneke   Nicolaï Johan   Augustijns Patrick   Annaert Pieter  

Expert Opinion on Drug Metabolism and Toxicology, Vol. 9, Iss. 5, 2013-05 ,pp. : 589-616

Informa Healthcare

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Evaluation of the endothelin receptor antagonists ambrisentan, darusentan, bosentan, and sitaxsentan as substrates and inhibitors of hepatobiliary transporters in sandwich-cultured human hepatocytes

By Hartman J. C.   Brouwer Kenneth   Mandagere Arun   Melvin Lawrence   Gorczynski Richard  

Canadian Journal of Physiology and Pharmacology, Vol. 88, Iss. 6, 2010-06 ,pp. : 682-691

NRC Research Press

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Sandwich-cultured hepatocytes: an in vitro model to evaluate hepatobiliary transporter-based drug interactions and hepatotoxicity

By Swift* Brandon   Pfeifer* Nathan D.   Brouwer Kim L.R.  

Drug Metabolism Reviews, Vol. 42, Iss. 3, 2010-08 ,pp. : 446-471

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Gender Differences in P-Glycoprotein Expression and Function: Effects on Drug Disposition and Outcome

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Current Drug Metabolism, Vol. 10, Iss. 4, 2009-05 ,pp. : 322-328

Bentham Science Publishers

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FK506 (tacrolimus) increases rat 1 -acid glycoprotein expression in liver and primary cultured hepatocytes

By Shimoishi K.   Kai H.   Kabu K.   Komori T.   Maruyama T.   Otagiri M.  

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