

Author: L’Azou B. Dubus I. Ohayon-Courtès C. Cambar J.
Publisher: Springer Publishing Company
ISSN: 0742-2091
Source: Cell Biology and Toxicology, Vol.23, Iss.4, 2007-07, pp. : 267-278
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Abstract
Cadmium represents a major environmental pollutant that may induce severe damage, especially in the kidney where cadmium accumulates. While cadmium is known to severely impair renal tubular functions, glomerular structures are also potential targets. Owing to their contractile properties, glomerular mesangial cells play a major role in the control of glomerular hemodynamics and influence the ultrafiltration coefficient. Cell cultures provide alternative and fruitful models for study of
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