Author： Pucadyil Thomas Kalipatnapu Shanti Chattopadhyay Amitabha
Publisher： Springer Publishing Company
ISSN： 1053-0509
Source： Journal of Fluorescence, Vol.15, Iss.5, 2005-09, pp. : 785-796
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Abstract
The G-protein-coupled receptor (GPCR) superfamily represents one of the largest classes of molecules involved in signal transduction across the plasma membrane. Fluorescence-based approaches have provided valuable insights into GPCR functions such as receptor–receptor and receptor–ligand interactions, real-time assessment of signal transduction, receptor dynamics on the plasma membrane, and intracellular trafficking of receptors. This has largely been possible with the use of fluorescent probes such as the green fluorescent protein (GFP) from the jellyfish
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