The replication of canine herpesvirus (CHV) induces apoptosis in canine kidney cell line: Short communication

Author: Kim O.   Yi S. J.  

Publisher: Akademiai Kiado

ISSN: 0236-6290

Source: Acta Veterinaria Hungarica, Vol.53, Iss.1, 2005-01, pp. : 147-151

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

The alphaherpesvirus canine herpesvirus (CHV) was tested in order to determine whether or not it has apoptotic potential. We have demonstrated that lytic replication of CHV resulted in induction of apoptosis. This phenomenon was confirmed using different techniques including in situ TUNEL assay and DNA laddering. The apoptotic activity of CHV might influence the pathobiology of this virus.