Cationic Inhibitors of Serine Proteinases from Buckwheat Seeds: Study of Their Interaction with Exogenous Proteinases

Author： Tsybina T. A.   Dunaevsky Y. E.   Popykina N. A.   Larionova N. I.   Belozersky M. A.  

Publisher： MAIK Nauka/Interperiodica

ISSN： 0006-2979

Source： Biochemistry (Moscow), Vol.69, Iss.4, 2004-04, pp. : 441-444

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Abstract

The inhibition of exogenous serine proteinases of different origin by cationic protease inhibitors BWI-1c, -2c, -3c, and -4c from buckwheat (Fagopyrum esculentum Moench) seeds has been studied. High efficiency of the inhibitors in binding bovine trypsin and chymotrypsin as well as their broad antiprotease effect, including inhibition of proteinases secreted by fungi and bacteria, has been demonstrated. According to the data obtained, it is proposed that cationic inhibitors from buckwheat seeds may participate in the defense of plants against fungal and bacterial infection.

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