Antiphospholipid syndrome: a series of surgical emergencies and the current evidence for its management

Author: Agaba AE   Charaklias N   Babu-Victor A   Agaba PO   Deepchand V   Dabasia HS   Sharma SS   Goodrick MJ   Ramanand B  

Publisher: The Royal College of Surgeons of England

ISSN: 1478-7083

Source: Annals of The Royal College of Surgeons of England, Vol.88, Iss.4, 2006-07, pp. : 370-374

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Abstract

It is generally accepted that antiphospholipid syndrome remains a major medical problem characterised by hypercoagulability, arterial and venous thrombosis and thrombocytopenia. It is unclear how best to treat these patients should they require emergency surgery. If a lupus anticoagulant is present, hypercoagulability may occur de novo but surgical interventions along with sepsis are two important predisposing factors. We describe three patients with primary antiphospholipid syndrome and discuss the implications for surgery.