Author: Rasbach Daniel A. Desruisseau Andrew J. Kipp Aaron M. Stinnette Samuel Kheshti Asghar Shepherd Bryan E. Sterling Timothy R. Hulgan Todd McGowan Catherine C. Qian Han-Zhu
Publisher: Routledge Ltd
ISSN: 1360-0451
Source: AIDS Care, Vol.25, Iss.1, 2013-01, pp. : 109-117
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Abstract
Clarifying the relationship between illicit drug use and HIV-1 virologic suppression requires characterization of both illicit drug use activity and adherence to antiretroviral therapy (ART). We developed a rapid clinical questionnaire to assess prior 7-day illicit drug use and ART adherence in a cross-sectional study among 1777 HIV-infected persons in care. Of these, 76% were male, 35% were African-American, and 8% reported injection drug use as their probable route of HIV-1 infection. Questionnaire-reported frequencies of cocaine and marijuana use within the previous 7 days were 3.3% and 12.1%, respectively. Over three quarters (77.8%) of participants were on ART, of whom 69.7% had HIV-1 virologic suppression (HIV-1 RNA<48 copies/mL). Univariate analyses revealed that compared to no use, cocaine and marijuana use were both associated with missed ART doses (