beta -Mannosidosis in a Salers calf: a new storage disease of cattle

Author: Jolly RD   Thompson KG   Bayliss SL   Vidler BM   Orr MB   Healy PJ  

Publisher: Taylor & Francis Ltd

ISSN: 1176-0710

Source: New Zealand Veterinary Journal, Vol.38, Iss.3, 1990-09, pp. : 102-105

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Abstract

A storage disease characterised by widespread vacuolation of cells throughout the body was diagnosed in a newborn calf of the Salers breed. Extraction and analyses of water soluble material showed that the storage material was oligosaccharide in nature and was probably derived from the core region of the heterosaccharide moiety of glycoproteins. Glycosidase analyses showed that the disease was due to a deficiencv of acidic β-mannosidase.