Perinatal and familial risk factors for acute lymphoblastic leukemia in a Swedish national cohort

Publisher: John Wiley & Sons Inc

ISSN: 0008-543x

Source: CANCER, Vol.121, Iss.7, 2015-04, pp. : 1040-1047

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Abstract

The authors conducted what, to their knowledge, is the largest population‐based cohort study to date to examine perinatal and familial risk factors for acute lymphoblastic leukemia (ALL) among approximately 3.5 million individuals born in Sweden between 1973 and 2008. High fetal growth was found to be associated with an increased risk of ALL in childhood through young adulthood, independent of gestational age at birth, suggesting that growth factor pathways may play an important long‐term role in the etiology of ALL.