Utility of free and total target measurements as target engagement and efficacy biomarkers in biotherapeutic development—Opportunities and challenges

Publisher： John Wiley & Sons Inc

E-ISSN： 1552-4604|55|S3|S75-S84

ISSN： 0091-2700

Source： JOURNAL OF CLINICAL PHARMACOLOGY (ELECTRONIC), Vol.55, Iss.S3, 2015-03, pp. : S75-S84

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

Related content

A summary of meeting proceedings for ‘Measuring immune responses in non-human primates for drug development—Opportunities and challenges for predicting human efficacy and immunotoxicity’

By Kamperschroer Cris   Kaur Amitinder   Lebrec Hervé  

Journal of Immunotoxicology, Vol. 9, Iss. 1, 2012-03 ,pp. : 108-120

Informa Healthcare

Access to resources Recommend Favorite

EEG biomarkers of target engagement, therapeutic effect, and disease process

By  

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, Vol. 1344, Iss. 1, 2015-05 ,pp. : 12-26

John Wiley & Sons Inc

Access to resources Recommend Favorite

Rho kinase as potential therapeutic target for cardiovascular diseases: opportunities and challenges

By Hu Erding   Lee Dennis  

Expert Opinion on Therapeutic Targets, Vol. 9, Iss. 4, 2005-08 ,pp. : 715-736

Informa Healthcare

Access to resources Recommend Favorite

TARGET2-Securities: What are the challenges and opportunities for CSDs and custodians?

By Rosenkranz Katja   Kindler Tomas  

Journal of Securities Operations & Custody, Vol. 1, Iss. 1, 2007-10 ,pp. : 41-52

Henry Stewart Publications

Access to resources Recommend Favorite

Analytical assay platforms for soluble target engagement biomarkers: old favorites and emerging technologies

By Goodman Joanne   Agoram Balaji  

Bioanalysis, Vol. 5, Iss. 23, 2013-12 ,pp. : 2919-2931

Future Science

Access to resources Recommend Favorite