Natural Products: Promising Resources for Cancer Drug Discovery

Publisher: Bentham Science Publishers

E-ISSN: 1875-5992|12|1|49-75

ISSN: 1871-5206

Source: Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry - Anti-Cancer Agents), Vol.12, Iss.1, 2012-01, pp. : 49-75

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Abstract

Natural products are important sources of anti-cancer lead molecules. Many successful anti-cancer drugs are natural products or their analogues. Many more are under clinical trials. The present review focuses on chemopreventive and anti-cancer activities of polar and non-polar extracts, semi purified fractions and pure molecules from terrestrial plants of India reported between 2005 and 2010 emphasizing possible mechanisms of action of pure molecules.