The Modular Synthesis of Chiral N-Heterocyclic Carbene Precursors

Publisher: Bentham Science Publishers

E-ISSN: 1875-6255|4|8|563-566

ISSN: 1570-1786

Source: Letters in Organic Chemistry, Vol.4, Iss.8, 2007-12, pp. : 563-566

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Abstract

A series of chiral N-heterocyclic carbene precursors based on the dihydroimidazole framework were prepared from easily available chiral amines. The sequential attachment of these amines and mesitylamine to chloroacetyl chloride followed by reduction and subsequent ring closure gave the desired dihydroimidazolium salts in good yield.

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