Design, Synthesis, and Application of Peptide Secondary Structure Mimetics

Publisher： Bentham Science Publishers

E-ISSN： 1875-5607|2|5|447-462

ISSN： 1389-5575

Source： Mini Reviews in Medicinal Chemistry, Vol.2, Iss.5, 2002-10, pp. : 447-462

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

The secondary structure peptidomimetic approach is a rational way to develop novel nonpeptide pharmaceutical agents based upon biologically significant proteinaceous leads. A part of this approach elaborated in this laboratory over the past ten years is reviewed along with the recent developments in this field.

Related content

Structure-Based Drug Design of Peptide Mimetics Containing Large P3 Moieties as Inhibitors of Factor VIIa

By  

Letters in Drug Design & Discovery, Vol. 6, Iss. 2, 2009-03 ,pp. : 86-92 (7)

Bentham Science Publishers

Access to resources Recommend Favorite

Tandem Repeat Peptide Strategy for the Design of Neurotrophic Factor Mimetics

By  

CNS & Neurological Disorders - Drug Targets (Formerly Current Drug Targets - CNS & Neurological Disorders), Vol. 7, Iss. 1, 2008-02 ,pp. : 110-119 (10)

Bentham Science Publishers

Access to resources Recommend Favorite

Mimetics of the Peptide &bgr;-Strand

By  

Mini Reviews in Medicinal Chemistry, Vol. 2, Iss. 5, 2002-10 ,pp. : 433-445 (13)

Bentham Science Publishers

Access to resources Recommend Favorite

Peptide Mimetics of Neurotrophins and their Receptors

By  

Current Pharmaceutical Design, Vol. 17, Iss. 25, 2011-08 ,pp. : 2704-2718 (15)

Bentham Science Publishers

Access to resources Recommend Favorite

Applications of Peptide Mimetics in Cancer

By  

Current Medicinal Chemistry, Vol. 9, Iss. 4, 2002-02 ,pp. : 411-420 (10)

Bentham Science Publishers

Access to resources Recommend Favorite