Publisher： Bentham Science Publishers
E-ISSN： 1875-5402|11|7|505-513
ISSN： 1386-2073
Source： Combinatorial Chemistry & High Throughput Screening, Vol.11, Iss.7, 2008-08, pp. : 505-513
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
Abstract
A fluorescent probe is a fluorophore designed to localize within a specific region of a biological specimen or to respond to a specific stimulus. Fluorescent probes have been used for nearly a century to study cellular processes due to their exquisite sensitivity and selectivity. Fluorescent probes have also gained in popularity as safety and environmental concerns over the use of radioactive probes have grown. At the same time, cellular assays are being more widely used now than ever before. This review will give a broad overview of types of fluorescent probes, types of fluorescent assays, and their application in cellular assays for a number of pharmaceutically relevant target classes.
Related content
Fluorescent Probes and Labels for Cellular Imaging
CHIMIA International Journal for Chemistry, Vol. 63, Iss. 11, 2009-11 ,pp. :
Access to resources
Recommend
The Development of Fluorescent Probes for Visualizing Intracellular Hydrogen Polysulfides
ANGEWANDTE CHEMIE, Vol. 127, Iss. 47, 2015-11 ,pp. :