Assessment of Competitive and Mechanism-Based Inhibition by Clarithromycin: Use of Domperidone as a CYP3A Probe-Drug Substrate and Various Enzymatic Sources Including a New Cell-Based Assay with Freshly Isolated Human Hepatocytes

Publisher： Bentham Science Publishers

E-ISSN： 1874-0758|4|2|69-76

ISSN： 1872-3128

Source： Drug Metabolism Letters, Vol.4, Iss.2, 2010-04, pp. : 69-76

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

Related content

Mechanism-Based Inhibition of Zinc Proteases

By  

Current Medicinal Chemistry, Vol. 8, Iss. 8, 2001-07 ,pp. : 959-965

Bentham Science Publishers

Access to resources Recommend Favorite

Mechanism-Based Inhibition of Cytochrome P450 3A4 by Therapeutic Drugs

By Zhou Shufeng  

Clinical Pharmacokinetics, Vol. 44, Iss. 3, 2005-01 ,pp. : 279-304

Adis International

Access to resources Recommend Favorite

Opportunities and limits of cell-based assay miniaturization in drug discovery

By Carstens Cornelia   Elbracht Rudi   Gärtner Claudia   Becker Holger  

Expert Opinion on Drug Discovery, Vol. 5, Iss. 7, 2010-07 ,pp. : 673-679

Informa Healthcare

Access to resources Recommend Favorite

Cree antidiabetic plant extracts display mechanism-based inactivation of CYP3A4

By Tam Teresa W.   Liu Rui   Arnason John T.   Krantis Anthony   Staines William A.   Haddad Pierre S.   Foster Brian C.  

Canadian Journal of Physiology and Pharmacology, Vol. 89, Iss. 1, 2011-01 ,pp. : 13-23

NRC Research Press

Access to resources Recommend Favorite

Prediction of Drug-Drug Interactions Arising From Mechanism-Based Inactivation: Key Input Parameters and Impact on Risk Assessment

By  

Current Drug Metabolism, Vol. 12, Iss. 9, 2011-11 ,pp. : 871-890

Bentham Science Publishers

Access to resources Recommend Favorite