Publisher： Bentham Science Publishers
E-ISSN： 1875-6727|2|1|51-58
ISSN： 1573-4110
Source： Current Analytical Chemistry, Vol.2, Iss.1, 2006-01, pp. : 51-58
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Abstract
The determination of superoxide anion (O2 .-) is of great physiological and pathological importance since O2 .- is considered to be involved in the etiology of aging, cancer, and progressive neurodegenerative diseases such as Parkinson's disease. The determination of the local concentration of O2 .- has been a relatively challenging analytical problem because of the low concentration, high reactivity and short lifetime of O2 .- in biological systems. This review raises a number of methods, highlighting electrochemical methodologies, for the determination of O2 .-. These electrochemical sensors and biosensors and their analytical characteristics are discussed in detail.
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