Capillary Electrophoresis with Mass Spectrometry: Applications to Metabolomic Analysis

Publisher： Bentham Science Publishers

E-ISSN： 2213-2368|1|2|121-127

ISSN： 2213-235X

Source： Current Metabolomics, Vol.1, Iss.2, 2013-04, pp. : 121-127

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

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Abstract

The use of capillary electrophoresis with mass spectrometry (CE-MS) for metabolomic analysis has substantially increased in recent years. This hyphenated technique takes full advantage of the high separation efficiency of CE and the identification capability of MS, providing a powerful tool for rapid analysis and identification of metabolites in complex biological samples. This article focuses on an overview of some recent applications of CE-MS in metabolomics studies. We also discuss the techniques for the coupling of CE with MS and the potential of 2-D CE-MS for metabolomic analysis.

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