Platelet ADP Receptors and their Antagonists

Publisher: Bentham Science Publishers

E-ISSN: 1875-5607|3|2|145-148

ISSN: 1389-5575

Source: Mini Reviews in Medicinal Chemistry, Vol.3, Iss.2, 2003-03, pp. : 145-148

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Abstract

ADP plays a crucial role in haemostasis and thrombosis and its receptors are potential target for antithrombotic drugs.The knowledge of the ADP-receptors has been amplified by recent discoveries. This review highlights the ADP-receptors models and their antagonists described in the recent literature, mainly the thienopyridine derivatives.