Publisher： Bentham Science Publishers
E-ISSN： 1873-4294|14|10|1225-1234
ISSN： 1568-0266
Source： Current Topics in Medicinal Chemistry, Vol.14, Iss.10, 2014-05, pp. : 1225-1234
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Abstract
-Methylisoserine, a chiral acyclic quaternary &bgr;-amino acid, has been used to mimic secondary structures, when it is incorporated in a homogeneous &bgr;2,2-dipeptide. In particular, the observed folded conformations in aqueous solution can be regarded as mimics of &bgr;-turn.
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