Organic Modification of the Polysaccharide Alginate

Publisher: Bentham Science Publishers

E-ISSN: 1875-6298|7|1|61-67

ISSN: 1570-193X

Source: Mini-Reviews in Organic Chemistry, Vol.7, Iss.1, 2010-02, pp. : 61-67

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Abstract

The polysaccharide alginate is a linear chain binary copolymer made of guluronic acid and mannuronic acid subunits. Alginate is a natural polymer material produced by a number of organisms, including brown algae and bacteria. It has found application in a variety of areas, including food, cosmetics, pharmaceutical and biomedical industries. In recent years, a number of studies have been published on covalent modification of alginate, often through carbodiimide-mediated reactions at the carboxyl moieties. These modifications have imparted a wide range of different chemical and physical material properties, including altered reactivity, hydrophilicity, viscosity and sorption characteristics. This mini-review focuses on the methods and applications of organically modified alginates from recent publications.