Kappa, a mischievous monster found in Japanese folklore, supposedly lives in a stream or pond, and has webbed hands and feet so that it's good at swimming. Human hands also have an interdigital web in the early embryo, but it disappears by apoptotic programmed cell death like a tadpole's tail. The intracellular signaling pathway that triggers apoptosis has been studied well; the signal flows down the ‘cascade’ that consists of multiple caspases (Cysteine‐ASPartic proteASE) such as caspase 9 or 3 encoded by CASP9 or CASP3, respectively. This poor Kappa in this drawing has been saturated with the water flowing down the caspase cascade, and its vaunted web is in danger of disappearing by apoptosis. Designed by TRAIS Co., Ltd. (Kobe, Japan)

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GENES TO CELLS, Vol. 20, Iss. 10, 2015-10 ,pp. : i-i

John Wiley & Sons Inc

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Kappa, a mischievous monster found in Japanese folklore, supposedly lives in a stream or pond, and has webbed hands and feet so that it's good at swimming. Human hands also have an interdigital web in the early embryo, but it disappears by apoptotic programmed cell death like a tadpole's tail. The intracellular signaling pathway that triggers apoptosis has been studied well; the signal flows down the ‘cascade’ that consists of multiple caspases (Cysteine‐ASPartic proteASE) such as caspase 9 or 3 encoded by CASP9 or CASP3, respectively. This poor Kappa in this drawing has been saturated with the water flowing down the caspase cascade, and its vaunted web is in danger of disappearing by apoptosis. Designed by TRAIS Co., Ltd. (Kobe, Japan)

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GENES TO CELLS, Vol. 1356-9597, Iss. 10, 2015-10 ,pp. : i-i

John Wiley & Sons Inc

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Evolutionary analyses of caspase‐8 and its paralogs: Deep origins of the apoptotic signaling pathways

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BIOESSAYS (ELECTRONIC), Vol. 37, Iss. 7, 2015-07 ,pp. : 767-776

John Wiley & Sons Inc

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Isorhynchophylline, a Potent Plant Alkaloid, Induces Apoptotic and Anti-Metastatic Effects in Human Hepatocellular Carcinoma Cells through the Modulation of Diverse Cell Signaling Cascades

By Lee Hanwool   Baek Seung Ho   Lee Jong Hyun   Kim Chulwon   Ko Jeong-Hyeon   Lee Seok-Geun   Chinnathambi Arunachalam   Alharbi Sulaiman Ali   Yang Woong Mo   Um Jae-Young   Sethi Gautam   Ahn Kwang Seok  

International Journal of Molecular Sciences, Vol. 18, Iss. 5, 2017-05 ,pp. : 1095-1095

MDPI

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Conserved Features and Evolutionary Shifts of the EDA Signaling Pathway Involved in Vertebrate Skin Appendage Development

By Pantalacci Sophie   Chaumot Arnaud   Benot Grard   Sadier Alexa   Delsuc Frdric   Douzery Emmanuel J. P.   Laudet Vincent  

Molecular Biology and Evolution, Vol. 25, Iss. 5, 2008-05 ,pp. : 912-928

Oxford University Press

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