Facial Erythema and Pigmentation as an Initial Manifestation of Chronic Graft‐versus‐Host Disease

Publisher: John Wiley & Sons Inc

E-ISSN: 1346-8138|21|3|185-188

ISSN: 0385-2407

Source: THE JOURNAL OF DERMATOLOGY, Vol.21, Iss.3, 1994-03, pp. : 185-188

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Abstract

AbstractTwo bone marrow transplant recipients developed chronic graft‐versus‐host disease, presenting with a mild erythematous, pigmented eruption only on the face three and ten months after transplantation. Histologically, the lesions showed liquefaction degeneration of basal keratinocytes and incontinence of melanin in the upper dermis with a mild infiltrate of T‐lymphocytes. These findings suggest that such a facial eruption occasionally may represent an initial manifestation of chronic GVHD.