Reactions in Leprosy

E-ISSN： 1346-8138|15|5|412-419

ISSN： 0385-2407

Source： THE JOURNAL OF DERMATOLOGY, Vol.15, Iss.5, 1988-10, pp. : 412-419

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

AbstractThe clinical manifestations of types I (lepra) and II (ENL) reactions are now well‐appreciated. The correlation of clinical expression to bacterial index, lepromin response and histological features has hardly been attempted. In a study of 35 reaction patients, 18 type I (lepra) and 17 type II (ENL), the preceding parameters were studied in detail. Their incidence among leprosy patients was 20%. Males in the age group 20–30 years were frequently affected, the ratio of males to females being 6:1. The mean age at onset in type II (ENL) was younger than in type I (lepra) reactions. However, the duration of the reactions was variable. They were frequently precipitated by antileprosy drugs. The clinical features were cardinal. The bacteriological features reflected wide variations, but were considered imperative. Early Fernandez and Late Mitsuda reactions were useful adjuvants for monitoring progress. The utility of changing microscopic pathology in determining the swing towards the lepromatous or tuberculoid end of leprosy spectrum are emphasized.