Publisher： John Wiley & Sons Inc
E-ISSN： 1346-8138|21|10|741-745
ISSN： 0385-2407
Source： THE JOURNAL OF DERMATOLOGY, Vol.21, Iss.10, 1994-10, pp. : 741-745
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Abstract
AbstractMeasles skin rash was immunohistochemically examined in an effort to detect virus antigen in skin samples taken from a 15‐year‐old girl with measles. A sectioned specimen obtained by punch biopsy from a 2nd‐day skin lesion showed localized parakeratosis and acanthosis with multinucleated giant cells in the epidermis, thickening and cellular edema of epithelia in the hair follicles, and vascular dilatation in the papillary plexus. Measles virus antigen was detected by ABC immunoperoxidase in the epidermis, follicular epithelia, and lympho‐histiocytic cell infiltrates in the upper part of the dermis. This rash was deemed to be caused in part by direct viral infection of the epidermal cells.
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