Publisher： John Wiley & Sons Inc
E-ISSN： 1613-6829|11|36|4643-4650
ISSN： 1613-6810
Source： SMALL, Vol.11, Iss.36, 2015-09, pp. : 4643-4650
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Abstract
Living‐cell‐based screens can facilitate lead discovery of functional therapeutics of interest. A versatile and scalable method is reported that uses dense arrays of nanowells for imparting defined patterns on monolayers of cells. It is shown that this approach can coordinate a multi‐component biological assay by designing and implementing a high‐throughput, functional nanoliter‐scale neutralization assay to identify neutralizing antibodies against HIV.
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