Publisher： John Wiley & Sons Inc
E-ISSN： 1744-3091|66|12|1662-1665
ISSN： 1744-3091
Source： Acta Crystallographica Section F, Vol.66, Iss.12, 2010-12, pp. : 1662-1665
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Abstract
A secreted lectin, Rv1419, from Mycobacterium tuberculosis has been cloned, expressed, purified and crystallized and the crystals have been characterized. This represents the first X‐ray investigation of a lectin or lectin‐like molecule from the pathogen. The cubic crystals contain one molecule in the asymmetric unit. Sequence comparisons indicate that the lectin has a β‐trefoil fold and belongs to a well characterized family of carbohydrate‐binding modules. Structural analysis of the crystals is in progress.
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