Author： Arumanayagam Mano Feng Chi Cockram Clive Swaminathan Swami
Publisher： Ashgate Publishing Ltd
ISSN： 0031-3025
Source： Pathology, Vol.26, Iss.3, 1994-07, pp. : 291-293
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
Abstract
The mechanism by which erythrocyte mean corpuscular volume (MCV) is decreased in hyperthyroidism is not known. One possible mechanism is premature aging of erythrocytes in the circulation. Since erythrocyte creatine has been shown to be a good marker of cell senescence, we determined this in hyperthyroid patients and control subjects to examine whether the decrease in MCV is related to senescence. Erythrocyte creatine levels were similar in both hyperthyroid patients and controls, suggesting that premature senescence of erythrocytes does not account for the lower MCV in hyperthyroidism.
Related content
By Carr Marcus E. Masullo Lawrence N. Brown J. Kendall Lewis AN USA Paul C.
Military Medicine, Vol. 174, Iss. 6, 2009-06 ,pp. :
Access to resources
Recommend
Effects of Creatine Supplementation on Exercise Performance
Sports Medicine, Vol. 28, Iss. 1, 1999-07 ,pp. :