Synthesis, Chemical Characterization, DNA Interaction and Antioxidant, Studies of New Nitrosubstituted Thioureas and Their Copper Complexes

Publisher： John Wiley & Sons Inc

E-ISSN： 2192-6549|62|11|1020-1027

ISSN： 0009-4536

Source： JOURNAL OF THE CHINESE CHEMICAL SOCIETY (ELECTRONIC), Vol.62, Iss.11, 2015-11, pp. : 1020-1027

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Abstract

AbstractIn the present work new nitro substituted thioureas, and their copper complexes have been synthesized and characterized by FTIR and multinuclear NMR techniques. Some of the compounds namely 1‐benzoyl‐3‐(4‐chloro‐3‐nitrophenyl) thiourea (A‐1), 1‐benzoyl‐3‐(4‐chloro‐3‐nitrophenyl) thiourea (A‐2) and 1‐benzoyl‐3‐(2‐methoxy‐4‐nitrophenyl) thiourea (A‐2) have also been characterized by single crystal XRD. All the synthesized compounds have been screened for DNA binding potencies (using cyclic voltametry, UV‐vis spectroscopy) and free radical scavanging activities.

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