A novel DNA computing model based on RecA-mediated triple-stranded DNA structure

Author: Gang Fang   Shemin Zhang   Yafei Dong   Jin Xu  

Publisher: Taylor & Francis Ltd

ISSN: 1002-0071

Source: Progress in Natural Science, Vol.17, Iss.6, 2007-06, pp. : 708-711

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Abstract

The field of DNA computing emerged in 1994 after Adleman's paper was published. Henceforth, a few scholars solved some noted NP-complete problems in this way. And all these methods of DNA computing are based on conventional Watson-Click hydrogen bond of doublehelical DNA molecule. In this paper, we show that the triple-stranded DNA structure mediated by RecA protein can be used for solving computational problems. Sequence-specific recognition of double-stranded DNA by oligonucleotide-directed triple helix (triplex) formation is used to carry out the algorithm. We present procedure for the 3-vertex-colorability problems. In our proposed procedure, it is suggested that it is possible to solve more complicated problems with more variables by this model.