Brain penetration of methadone (R)- and (S)-enantiomers is greatly increased by P-glycoprotein deficiency in the blood–brain barrier of Abcb1a gene knockout mice

Author： Wang Jun-Sheng   Ruan Ying   Taylor Robin   Donovan Jennifer   Markowitz John   DeVane C.  

Publisher： Springer Publishing Company

ISSN： 0033-3158

Source： Psychopharmacology, Vol.173, Iss.1-2, 2004-04, pp. : 132-138

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