Hybrid 4‐Aminoquinoline‐1,3,5‐triazine Derivatives: Design, Synthesis, Characterization, and Antibacterial Evaluation

Publisher： John Wiley & Sons Inc

E-ISSN： 1943-5193|52|4|1108-1113

ISSN： 0022-152x

Source： JOURNAL OF HETEROCYCLIC CHEMISTRY, Vol.52, Iss.4, 2015-07, pp. : 1108-1113

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

A series of novel 4‐aminoquinoline 1,3,5‐triazine derivatives were synthesized and characterized by FTIR, 1H‐NMR, 13C‐NMR, MS, and elemental analysis. The antibacterial activities of synthesized compounds were tested against three Gram‐positive bacteria, namely Bacillus subtilis (NCIM‐2063), Bacillus cereus (NCIM‐2156), and Staphylococcus aureus (NCIM‐2079), and four Gram‐negative bacteria, namely Proteus vulgaris (NCIM‐2027), Proteus mirabilis (NCIM‐2241), Escherichia coli (NCIM‐2065), and Pseudomonas aeruginosa (NCIM‐2036), using ciprofloxacin as reference standard drug. Results showed compound 9a and 9e as potent antibacterial agents against all bacterial strains except Bacillus cereus (NCIM‐2156). Copyright © 2014 HeteroCorporation

Related content

Design, Synthesis, and Biological Evaluation of Unconventional Aminopyrimidine, Aminopurine, and Amino‐1,3,5‐triazine Methyloxynucleosides

By  

CHEMMEDCHEM, Vol. 10, Iss. 2, 2015-02 ,pp. : 321-335 (15)

John Wiley & Sons Inc

Access to resources Recommend Favorite

Synthesis and Properties of the Derivatives of 2,4,6-Tris(Phenoxy)-1,3,5-Triazine

By Dainyte Aiste   Gudeika Dalius   Buika Gintaras   Grazulevicius Juozas Vidas  

Molecular Crystals and Liquid Crystals, Vol. 590, Iss. 1, 2014-02 ,pp. : 73-79 (7)

Taylor & Francis Ltd

Access to resources Recommend Favorite

New methodology for automated SPOT synthesis of peptides on cellulose using 1,3,5‐triazine derivatives as linkers and as coupling reagents

By  

JOURNAL OF PEPTIDE SCIENCE (ELECTRONIC), Vol. 24, Iss. 2, 2018-02 ,pp. : n/a-n/a (NaN)

John Wiley & Sons Inc

Access to resources Recommend Favorite

Synthesis and characterization of a trefoil-shaped liquid crystal based on 1,3,5-triazine with carbazole groups

By Bai R.   Li S.   Zou Y.   Pan C.   Xie P.   Kong B.   Zhou X.   Zhang R.  

Liquid Crystals, Vol. 28, Iss. 12, 2001-12 ,pp. : 1873-1876 (4)

Taylor & Francis Ltd

Access to resources Recommend Favorite

Synthesis and crystal structure of 3,5-di(2-propenyl)-6-phenyl-1,3,5-triazine-2,4-dione and 2-dimethylamino-4-ethoxycarbonylmethoxy-6-phenyl-1,3,5-triazine

By Qing-Min Wang   Gang Liu   Rui-Lian Shao   Run-Qiu Huang  

Journal of Chemical Crystallography, Vol. 34, Iss. 1, 2004-01 ,pp. : 31-37 (7)

Springer Publishing Company

Access to resources Recommend Favorite