Frequencies of lymphoid T‐follicular helper cells obtained longitudinally by lymph node fine‐needle aspiration correlate significantly with viral load in SIV‐infected rhesus monkeys

Publisher： John Wiley & Sons Inc

E-ISSN： 1600-0684|44|5|253-262

ISSN： 0047-2565

Source： JOURNAL OF MEDICAL PRIMATOLOGY, Vol.44, Iss.5, 2015-10, pp. : 253-262

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Abstract

T‐follicular helper (TFH) cells are an important population in lymph nodes (LNs) contributing to the generation of highly specific B cells. For SIV studies in rhesus macaques (RM), analysis of LN is necessary, but restricted due to invasive sampling. We applied the minimally invasive LN fine‐needle aspiration (LN‐FNA) and examined dynamics of TFH cells during SIV infection.

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