Using Nanotech Radiopharmaceutical for the Visualization of Sentinel Lymph Nodes in Patients with Cervical Cancer

E-ISSN： 1662-8985|2015|1084|540-544

ISSN： 1022-6680

Source： Advanced Materials Research, Vol.2015, Iss.1084, 2015-02, pp. : 540-544

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Abstract

The study of radionuclide determination of SLN and optimization of surgical treatment in organ-sparing treatment of invasive cervical cancer included 26 patients with cervical cancer of stage I. To identify sentinel lymph nodes a nanocolloid was administered one day prior to the planned operation. Sentinel lymph nodes were identified in 26 patients. A comparative evaluation of the sensitivity of techniques for determining SLN, depending on the method, has showed that the SPECT sensitivity was 72%, with radiometry this indicator was 93.3%. The technique of intraoperative radiometric determination of SLN is more efficient in comparison with SPECT. The optimum is the combined use of both techniques, when the probability of SLN detection increases to 91.4%.